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The 114th Annual Meeting of the American Association for Cancer Research featured deep science and a robust multidisciplinary program united by the theme “Advancing the Frontiers of Cancer Science and Medicine,” which reflects the AACR’s commitment to operating at the cutting edge of cancer research and setting a standard for the field that will transform patient outcomes.
During the final session of the AACR Annual Meeting 2023, Program Committee Chair Robert H. Vonderheide, MD, DPhil, and three members of the Program Committee reviewed several significant highlights and important themes from the meeting.
Three experts discussed the evolution of phase I trials during an Annual Meeting symposium on Tuesday, April 18. “We must recognize that forward- and reverse-translation are complementary and phase I is the place to do it. The old linear model of moving forward and failing later is not serving us or our patients,” said Shivaani Kummar, MD.
A panel of physician-scientists from the U.S. and sub-Saharan Africa discussed the challenges of global cancer care and opportunities to improve outcomes in lower- and middle-income countries during a symposium on the final day of the Annual Meeting. Sharmila Anandasabapathy, MD, moderated the session.
During a unique Annual Meeting session, National Cancer Institute Director Monica M. Bertagnolli, MD (pictured), sat down with AACR President Lisa M. Coussens, PhD, FAACR, to discuss the NCI’s goals for the Cancer Moonshot initiative and the recently released National Cancer Plan.
Researchers reported promising results from five studies, including the first cancer vaccine trial to demonstrate clinical benefit in melanoma, which was reported by Jeffrey S. Weber, MD, PhD, during the first clinical trials plenary session at the Annual Meeting.
Sarah K. Tasian, MD, Jezabel Rodriguez-Blanco, PhD, and Corinne M. Linardic, MD, PhD, discussed advances in pediatric cancer research and therapeutics during a Sunday afternoon symposium.
An expert panel of cancer researchers, including Tomi Akinyemiju, PhD, showcased cutting-edge research in diverse fields of study that is opening up new frontiers in all areas of cancer research, from basic science and drug discovery to population science and health equity.
Three researchers — Makoto Nakanishi, MD, PhD, Masashi Narita, MD, PhD, and Clemens A. Schmitt, MD, PhD — discussed the relationship between cellular senescence and cancer during a Saturday morning educational session. “Cellular senescence is at the heart of tissue integrity and tissue homeostasis,” Schmitt said.