Carl H. June, MD, FAACR, recipient of the AACR Award for Lifetime Achievement in Cancer Research, will discuss how CAR T-cell therapy is advancing the treatment of cancers and rare diseases during his Sunday award lecture.

Carolyn R. Bertozzi, PhD, recipient of the AACR Award for Outstanding Achievement in Chemistry in Cancer Research, will review her research on glycocalyx for cancer immune therapy during her award lecture Sunday afternoon.

Alexander S. Baras, MD, PhD, Amin H. Nassar, MD, and Tali Mazor, PhD, demonstrated specific applications of Project GENIE genomic datasets and described how the increasing availability of large clinico-genomic datasets generated through routine cancer care affords the opportunity to conduct precision oncology research using observational data at scale.

Session chair Dafna Bar-Sagi, PhD, previews the Saturday afternoon plenary, which will review nearly 40 years of KRAS history — from its discovery in 1982 to the approval of sotorasib in 2021 — and examine current strategies and the future of treating KRAS-mutated cancers.

Timothy A. Yap, MD, PhD, and Shivaani Kummar, MD, preview the Annual Meeting’s four clinical trials plenary sessions, which will include important studies looking at the immune system, the treatment of rare cancers, novel antitumor strategies, and molecularly targeted therapeutics.

Annual Meeting Program Committee Chair Robert H. Vonderheide, MD, DPhil, shares a few highlights from Saturday’s schedule to help you plan your day.

The Annual Meeting program features dedicated sessions examining cancer mortality in certain populations and communities, the impact of location on health outcomes, and novel approaches to achieving cancer health equity. Robert A. Winn, MD, and John H. Stewart, MD, preview the sessions.

The AACR Annual Meeting 2023 scientific program features four sessions covering some of the latest advances in cancer detection and prevention. David W. Wetter, PhD, Francisco Cartujano Barrera, MD, and Marcia R. Cruz-Correa, MD, PhD, preview the sessions.

More than 30 oral and poster presentations at the AACR Annual Meeting 2023 will be simultaneously published as articles in AACR journals, reflecting the high number of meritorious abstracts submitted for presentation at the meeting.