Aviv Regev, PhD, FAACR; Jakob Nikolas Kather, MD, MSc; Benjamin F. Cravatt, PhD; and Carolyn R. Bertozzi, PhD, FAACR, described evolving and emerging technological advances—from cell atlases and artificial intelligence-based biomarkers to proteomics and bioorthogonal chemistry—that are driving new discoveries and new directions in cancer research.

Margaret A. Goodell, PhD, FAACR, presented how clonal hematopoiesis can drive tumor risk and resistance during a Saturday plenary session on discovery science in early cancer biology and interception.

Annual Meeting Program Chairs Keith T. Flaherty, MD, FAACR, and Christina Curtis, PhD, MSc, preview notable items on Monday’s schedule to help you plan your day.

Michael N. Pollak, MD, will chair a Monday symposium on novel and exciting data-driven insights on obesity, nicotine addiction, and suboptimal dietary patterns.

Charles W. M. Roberts, MD, PhD, will chair a Monday evening panel discussion on lessons learned from studies of simple genome cancers.

Monday forums will cover topics including financial hardship in cancer care; treatment and research capabilities in low-resource settings; new weight-loss drugs and the obesity-cancer axis; and optimizing cancer vaccines.