The AACR Annual Meeting 2026 will once again feature highlights from the latest in breast cancer research presented at the most recent San Antonio Breast Cancer Symposium (SABCS), which delivers state-of-the-art information on the experimental biology, etiology, prevention, diagnosis, and therapy of breast cancer to an international audience of academic and private physicians and researchers. The session, “Latest Advances in Translational Research from the 2025 San Antonio Breast Cancer Symposium,” will take place on Tuesday, April 21, in Room 30 on the upper level of the San Diego Convention Center from 10:15 to 11:40 a.m. PT.
The American Association for Cancer Research (AACR) is a proud co-sponsor of SABCS, which has provided a forum for foundational discoveries in breast cancer since 1978. This marks the third consecutive year of SABCS updates featured at the AACR Annual Meeting, reflecting AACR’s commitment to breast cancer research progress.
The SABCS session at this year’s Annual Meeting will include specially selected presentations from the December 2025 symposium, said Carlos L. Arteaga, MD, FAACR, of The University of Texas Southwestern Harold C. Simmons Comprehensive Cancer Center. Arteaga is a co-director of SABCS and a former President of AACR.
“SABCS features some terrific translational research, and this is an opportunity to cross-pollinate some of those excellent speakers’ talks at the AACR Annual Meeting,” said Session Co-chair Charles M. Perou, PhD, FAACR, of the University of North Carolina Lineberger Comprehensive Cancer Center, who was a member of the SABCS 2025 Executive Committee and who co-organized the session with Arteaga. “It’s a reflection of the fact that the more basic side of breast cancer research, represented by many studies from the Annual Meeting, goes hand-in-hand with the more clinical breast cancer research that SABCS tends to focus on.”
The presenters for the session at the AACR Annual Meeting 2026 were selected for outstanding translational investigations in key areas, Perou said. The session stands to offer particular insight to attendees who are curious about how their work fits in with current clinical challenges in breast cancer.
Continuing the exchange of sessions between the AACR Annual Meeting and SABCS provides opportunities for collaboration and multipronged approaches to breast cancer research, according to Perou, who notes that breast cancer deaths in women remain a substantial challenge. But that challenge, he said, can be overcome when basic, translational, and clinical researchers come together at sessions like this one: “The more people working to address breast cancer mortality, the better.”
“Latest Advances in Translational Research from the 2025 San Antonio Breast Cancer Symposium” will feature presentations from three speakers:
- Sherene Loi, MBBS, PhD, of Peter MacCallum Cancer Centre in Australia, will present “Parity and breastfeeding and immune responses in breast cancer,” which will cover T-cell memory and reprogramming dynamics in breastfeeding, along with implications for immune responses to breast cancer.
- Shom Goel, MBBS, PhD, of Peter MacCallum Cancer Centre, will speak to Rb-driven tumor suppression in his talk, “When tumor suppressors activate: Rb drives an estrogen receptor target program that challenges its canonical tumor suppressor function.” Goel and his collaborators have identified Rb’s role as a transcriptional activator in luminal breast cancer, and his talk will cover data that demonstrate Rb’s dual function, with implications for treating estrogen-receptor-positive breast cancer.
- Nolan Priedigkeit, MD, PhD, of Dana-Farber Cancer Institute, will deliver his presentation, “Leveraging driver and truncal fusion RNAs as therapeutic triggers with a programmable nucleic acid sensing system.” This work shows how Priedigkeit and colleagues used existing nucleic-acid-sensing technology to design an approach that targets cancer-associated RNA fusions.
For the most up-to-date information on session dates, times, and locations, check the Annual Meeting App and Online Itinerary Planner.
More from the AACR Annual Meeting 2026 »
View a photo gallery of scenes from San Diego, join the conversation on social media using the hashtag #AACR26, and read more coverage in AACR Annual Meeting News and on Cancer Research Catalyst, the official blog of the AACR.
